UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression
Abstract
An improved understanding of the biochemical alterations that accompany tumor progression and metastasis is necessary to inform the next generation of diagnostic tools and targeted therapies. Metabolic reprogramming is known to occur during the epithelial–mesenchymal transition (EMT), a process that promotes metastasis. Here, we identify metabolic enzymes involved in extracellular matrix remodeling that are upregulated during EMT and are highly...
Paper Details
Title
UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression
Published Date
Jul 15, 2019
Journal
Volume
39
Issue
15
Pages
3089 - 3101
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Notes
History