CRISPR Craze to Transform Cardiac Biology

CRISPR is an easily accessible, versatile and affordable genome editing tool. It can be used to modify basically any aspect of gene regulation both in vitro and in vivo.Novel knock-in and knockout animal models can be generated within one generation using CRISPR-based approaches.Pathogenic variants can now easily be reverted or introduced in human induced pluripotent stem cells, yielding isogenic controls.The modular nature of the CRISPR system...