Analysis ofPROCandPROS1single nucleotide polymorphisms in a thrombophilia family

Objective The aim of this study was to assess the association of single nucleotide polymorphisms (SNPs) in protein C ( PROC ) and protein S ( PROS1 ) genes with deep venous thrombosis (DVT) in a thrombophilia family. Methods DNA were extracted from blood of participants. Five PROC SNPs and 11 PROS1 SNPs were selected from the Hapmap and 1000 Genomes databases. The minor allele frequencies (MAFs) of SNPs in the thrombophilia family (Group I) and...