Synthesis, characterization and biological evaluation of some novel sulfonylthiosemicarbazides

Volume: 194, Issue: 12, Pages: 1164 - 1170
Published: Jul 1, 2019
Abstract
A series of thiosemicarbazides were synthesized and structurally characterized by spectroscopic techniques (NMR, FT-IR) besides elemental analysis. These compounds were evaluated for their cytotoxicity against human breast cancer cell line MCF7 and prostate cancer cell line PC3 and nonmalignant fibroblast L929 cell line by MTT assay. Among the compounds, N-[2-(4-chlorophenyl)ethyl]-2-[(4-methylphenyl)sulfonyl]hydrazinecarbothioamide (3d) and...
Paper Details
Title
Synthesis, characterization and biological evaluation of some novel sulfonylthiosemicarbazides
Published Date
Jul 1, 2019
Volume
194
Issue
12
Pages
1164 - 1170
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