Subclinical atherosclerosis and its progression are modulated byPLIN2through a feed‐forward loop between LXR and autophagy

Volume: 286, Issue: 6, Pages: 660 - 675
Published: Jul 29, 2019
Abstract
Background Hyperlipidaemia is a major risk factor for cardiovascular disease, and atherosclerosis is the underlying cause of both myocardial infarction and stroke. We have previously shown that the Pro251 variant of perilipin-2 reduces plasma triglycerides and may therefore be beneficial to reduce atherosclerosis development. Objective We sought to delineate putative beneficial effects of the Pro251 variant of perlipin-2 on subclinical...
Paper Details
Title
Subclinical atherosclerosis and its progression are modulated byPLIN2through a feed‐forward loop between LXR and autophagy
Published Date
Jul 29, 2019
Volume
286
Issue
6
Pages
660 - 675
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