PRDM14 and BLIMP1 control the development of chicken primordial germ cells
Abstract
The differentiation of primordial germ cells (PGCs) is a fundamental step in development. PR domain-containing protein 14 (PRDM14) and B lymphocyte-induced maturation protein 1 (BLIMP1) play pivotal roles in mouse PGC specification. In the present study, we assessed the roles of chicken orthologs of PRDM14 and BLIMP1 in PGC development. PRDM14 and BLIMP1 were expressed in blastodermal cells and PGCs. The in vivo knockdown of PRDM14 or BLIMP1 by...
Paper Details
Title
PRDM14 and BLIMP1 control the development of chicken primordial germ cells
Published Date
Nov 1, 2019
Journal
Volume
455
Issue
1
Pages
32 - 41
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