Systematic Development of Sandwich Immunoassays for the Plasma Secretome
Volume: 19, Issue: 15
Published: Jul 22, 2019
Abstract
The plasma proteome offers a clinically useful window into human health. Recent advances from highly multiplexed assays now call for appropriate pipelines to validate individual candidates. Here, a workflow is developed to build dual binder sandwich immunoassays (SIA) and for proteins predicted to be secreted into plasma. Utilizing suspension bead arrays, ≈1800 unique antibody pairs are first screened against 209 proteins with recombinant...
Paper Details
Title
Systematic Development of Sandwich Immunoassays for the Plasma Secretome
Published Date
Jul 22, 2019
Volume
19
Issue
15
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