Amino Acid Organotin Polymers from Diglycine-Synthesis, Structural Characterization and Initial Anticancer Activity

Poly(amine esters) were synthesized from reaction of organotin dichlorides with the dipeptide diglycine. The products were generally high polymers and produced in high yield with yield increasing as the organotin alkyl chain increases in length. Reaction is rapid. Bands characteristic of the formation of the Sn–O–(C=O) and Sn–NH are found in the infrared spectra of the product. MALDI MS and NMR results are consistent with the proposed structure....