Carnosine Essential For Cardiac Function. A Study With Knockout Rats For The Carnosine Synthase Gene

Volume: 51, Issue: 6S, Pages: 330 - 331
Published: Jun 1, 2019
Abstract
Carnosine is present in high concentrations in heart, where it appears to increase the sensitivity of the contractile apparatus to Ca2+. However, it is currently unknown whether this role is relevant to the cardiac physiology. PURPOSE: To evaluate the impact of the lack of carnosine on myocardial contractile function in rats knockout (KO) for the CARNS1 gene (carnosine synthase1). METHODS: We developed the first KO animal model for the CARNS1...
Paper Details
Title
Carnosine Essential For Cardiac Function. A Study With Knockout Rats For The Carnosine Synthase Gene
Published Date
Jun 1, 2019
Journal
Volume
51
Issue
6S
Pages
330 - 331
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