Synthesis, characterization, anticancer and antioxidant activity of new nickel(II) and copper(II) flavonoid complexes

Flavonoids are natural products which are known to have biological activity for human health. In this study, new mixed ligand complexes of Ni(II) and Cu(II) were synthesized by using flavonoid (quercetin or naringenin) and heterocyclic imine (2,2′:6′,2′′-terpyridine or 2,2ꞌ-bipyiridine) ligands. The new complexes are [Ni(narH-1)(terpy)Cl].4H2O (1, nar = naringenin, terpy = 2,2′:6′,2′′-terpyridine), [Cu(narH-1)(terpy)Cl].H2O (2), and...