Methodological Considerations for Calculating Ventilatory Efficiency from a Maximal Exercise Test in Apparently Healthy Adults

The slope of the relationship between ventilation rate (VE) and rate of carbon dioxide production (VCO2) known as ventilatory efficiency (VE /VCO2 slope), is associated with mortality in clinical populations and may have prognostic utility in apparently healthy adults. Despite its prognostic potential, there is currently no standardized method for calculating the VE/VCO2 slope in apparently healthy adults. PURPOSE: To compare how different...