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Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk

Published on Jun 29, 2019in Nutrients 4.17
· DOI :10.3390/nu11071493
Alicia Julibert2
Estimated H-index: 2
Maria del Mar Bibiloni11
Estimated H-index: 11
+ 50 AuthorsPredimed-Plus Investigators
Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55–75 years old, with overweight/obesity and MetS) in the PREvencion con DIeta MEDiterranea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3–1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.
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Published on Apr 1, 2019in International Journal of Epidemiology 7.34
Miguel A. Martínez-González85
Estimated H-index: 85
(University of Navarra),
Pilar Buil-Cosiales20
Estimated H-index: 20
(University of Navarra)
+ 41 AuthorsJulia Wärnberg4
Estimated H-index: 4
(RMIT: RMIT University)
Published on Dec 19, 2018in Nutrients 4.17
Yvette Beulen , Miguel A. Martínez-González85
Estimated H-index: 85
+ 16 AuthorsHelmut Schröder35
Estimated H-index: 35
A moderately high-fat Mediterranean diet does not promote weight gain. This study aimed to investigate the association between dietary intake of specific types of fat and obesity and body weight. A prospective cohort study was performed using data of 6942 participants in the PREDIMED trial, with yearly repeated validated food-frequency questionnaires, and anthropometric outcomes (median follow-up: 4.8 years). The effects of replacing dietary fat subtypes for one another, proteins or carbohydrate...
Published on Nov 16, 2018
Haris Riaz10
Estimated H-index: 10
(Cleveland Clinic),
Muhammad Khan13
Estimated H-index: 13
(John H. Stroger, Jr. Hospital of Cook County)
+ 7 AuthorsHaitham M. Ahmed10
Estimated H-index: 10
(Cleveland Clinic)
Importance Although dyslipidemia has been consistently shown to be associated with atherogenesis, an association between obesity and cardiovascular disease outcomes remains controversial. Mendelian randomization can minimize confounding if variables are randomly and equally distributed in the population of interest. Objective To assess evidence from mendelian randomization studies to provide a less biased estimate of any association between obesity and cardiovascular outcomes. Data Sources Syste...
Published on Oct 25, 2018in Nutrients 4.17
Evangelia Malakou1
Estimated H-index: 1
Manolis Linardakis19
Estimated H-index: 19
(UoC: University of Crete)
+ 4 AuthorsAngeliki Papadaki19
Estimated H-index: 19
(UoB: University of Bristol)
Adhering to the Mediterranean diet (MD) and physical activity (PA) public health guidelines have independently been linked to health benefits in adults. These behaviours form essential components of the traditional Mediterranean lifestyle. However, their combined effect on metabolic risk has not been systematically assessed. This systematic review with meta-analysis (PROSPERO; CRD42017073958) aimed to examine, for the first time, the combined effect of promoting the MD and PA compared with no tr...
Published on Sep 30, 2018in Nutrients 4.17
Hayley Billingsley3
Estimated H-index: 3
Salvatore Carbone14
Estimated H-index: 14
Carl J. Lavie82
Estimated H-index: 82
The role of dietary fat has been long studied as a modifiable variable in the prevention and treatment of noncommunicable cardiometabolic disease. Once heavily promoted to the public, the low-fat diet has been demonstrated to be non-effective in preventing cardiometabolic disease, and an increasing body of literature has focused on the effects of a relatively higher-fat diet. More recent evidence suggests that a diet high in healthy fat, rich in unsaturated fatty acids, such as the Mediterranean...
Published on Feb 1, 2018in European Journal of Clinical Nutrition 3.11
Carlos Celis-Morales19
Estimated H-index: 19
(Glas.: University of Glasgow),
Katherine M. Livingstone16
Estimated H-index: 16
(Newcastle University)
+ 24 AuthorsHannah Forster12
Estimated H-index: 12
(UCD: University College Dublin)
To identify predictors of obesity in adults and investigate to what extent these predictors are independent of other major confounding factors. Data collected at baseline from 1441 participants from the Food4Me study conducted in seven European countries were included in this study. A food frequency questionnaire was used to measure dietary intake. Accelerometers were used to assess physical activity levels (PA), whereas participants self-reported their body weight, height and waist circumferenc...
Published on Aug 21, 2017in Annual Review of Nutrition 8.42
Dong D. Wang19
Estimated H-index: 19
Frank B. Hu202
Estimated H-index: 202
Health effects of dietary fats have been extensively studied for decades. However, controversies exist on the effects of various types of fatty acids, especially saturated fatty acid (SFA), on cardiovascular disease (CVD). Current evidence supports that different types of dietary fatty acids have divergent effects on CVD risk, and the effects also depend strongly on the comparison or replacement macronutrient. A significant reduction in CVD risk can be achieved if SFAs are replaced by unsaturate...
Published on Mar 8, 2017in PLOS ONE 2.78
Nuria Rosique-Esteban3
Estimated H-index: 3
(URV: Rovira i Virgili University),
Andrés Díaz-López13
Estimated H-index: 13
(URV: Rovira i Virgili University)
+ 23 AuthorsAntonio Garcia-Rios22
Estimated H-index: 22
(UCO: University of Córdoba (Spain))
Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional...
Published on Mar 7, 2017in Annals of Internal Medicine 19.32
Hanna E. Bloomfield18
Estimated H-index: 18
(UMN: University of Minnesota),
Nancy Greer22
Estimated H-index: 22
(UMN: University of Minnesota)
+ 1 AuthorsJ Wilt75
Estimated H-index: 75
(UMN: University of Minnesota)
Published on Mar 1, 2017in The American Journal of Clinical Nutrition 6.57
Marta Guasch-Ferré20
Estimated H-index: 20
(URV: Rovira i Virgili University),
Nerea Becerra-Tomás8
Estimated H-index: 8
(URV: Rovira i Virgili University)
+ 16 AuthorsMiquel Fiol37
Estimated H-index: 37
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