Management of colonic complications of type IV Ehlers–Danlos syndrome: a systematic review and evidence‐based management strategy

Aim Type IV Ehlers Danlos Syndrome (EDS) is a connective tissue disorder affecting approximately 1 per 100,000‐200,000 people. Life expectancy is reduced secondary to spontaneous vascular rupture or colonic perforation. Surgery carries significant morbidity and mortality. While strategies to manage colonic perforation include primary repair with or without a defunctioning stoma, Hartmann’s procedure, total abdominal colectomy with end ileostomy...