Chronic lymphocytic leukaemia: from genetics to treatment
Abstract
Chronic lymphocytic leukaemia (CLL), the most frequent type of leukaemia in adults, is a lymphoproliferative disorder that is characterized by the expansion of monoclonal, mature CD5+CD23+ B cells in the peripheral blood, secondary lymphoid tissues and bone marrow. CLL is an incurable disease with a heterogeneous clinical course, for which the treatment decision still relies on conventional parameters (such as clinical stage and lymphocyte...
Paper Details
Title
Chronic lymphocytic leukaemia: from genetics to treatment
Published Date
Jul 5, 2019
Volume
16
Issue
11
Pages
684 - 701
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