Abstract 2108: Chromatin state as a mechanism of anthracycline response in breast cancer
Published: Jul 1, 2019
Abstract
The aim of this study is to determine the effect of chromatin regulators on anthracycline response in breast cancer. Anthracyclines are a highly effective component of curative breast cancer chemotherapy, but can be associated with substantial side effects. Because anthracyclines work in part via inhibition of topoisomerase II (TOP2) on accessible DNA, we hypothesized that expression levels of chromatin regulatory proteins that mediate DNA...
Paper Details
Title
Abstract 2108: Chromatin state as a mechanism of anthracycline response in breast cancer
Published Date
Jul 1, 2019
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