Vector-related stratagems for enhanced monoclonal antibody production in mammalian cells

Provision of effective monoclonal antibody (mAb) based therapeutics requires careful combination of expression, selection and screening, in a suitable cell culture platform. The cell culture platform, in turn, requires high performance expression vectors for consistent and high production of mAb-based therapeutics. Further, the components of the vector need to be optimized via genetic engineering approaches, to exclude non-productive clones,...