Sacituzumab govitecan (IMMU-132) in uterine serous carcinoma
Abstract
Objective: Uterine serous carcinoma (USC) is an aggressive variant of endometrial cancer with poor prognosis. Sacituzumab govitecan (IMMU-132) is a novel antibody-drug conjugate (ADC) targeting trophoblast antigen 2 (Trop-2), a cell surface glycoprotein highly expressed in many epithelial tumors including USC, to deliver SN-38, the active metabolite of irinotecan. The objective of this study was to preclinically evaluate the efficacy of IMMU-132...
Paper Details
Title
Sacituzumab govitecan (IMMU-132) in uterine serous carcinoma
Published Date
Jun 1, 2019
Journal
Volume
154
Pages
64 - 64
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Notes
History