Coevolution of Sites under Immune Selection Shapes Epstein–Barr Virus Population Structure

Volume: 36, Issue: 11, Pages: 2512 - 2521
Published: Jul 2, 2019
Abstract
Epstein-Barr virus (EBV) is one of the most common viral infections in humans and persists within its host for life. EBV therefore represents an extremely successful virus that has evolved complex strategies to evade the host's innate and adaptive immune response during both initial and persistent stages of infection. Here, we conducted a comparative genomics analysis on 223 whole genome sequences of worldwide EBV strains. We recover extensive...
Paper Details
Title
Coevolution of Sites under Immune Selection Shapes Epstein–Barr Virus Population Structure
Published Date
Jul 2, 2019
Volume
36
Issue
11
Pages
2512 - 2521
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