Targeting mitochondria‐associated membranes as a potential therapy against endothelial injury induced by hypoxia

Volume: 120, Issue: 11, Pages: 18967 - 18978
Published: Jun 26, 2019
Abstract
Mitochondrial dysfunction plays a principal role in hypoxia-induced endothelial injury, which is involved in hypoxic pulmonary hypertension and ischemic cardiovascular diseases. Recent studies have identified mitochondria-associated membranes (MAMs) that modulate mitochondrial function under a variety of pathophysiological conditions such as high-fat diet-mediated insulin resistance, hypoxia reoxygenation-induced myocardial death, and...
Paper Details
Title
Targeting mitochondria‐associated membranes as a potential therapy against endothelial injury induced by hypoxia
Published Date
Jun 26, 2019
Volume
120
Issue
11
Pages
18967 - 18978
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