An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
Abstract
The virulence of Pseudomonas aeruginosa, a Gram-negative opportunistic pathogen, is regulated by many transcriptional factors (TFs) that control the expression of quorum sensing and protein secretion systems. Here, we report a genome-wide, network-based approach to dissect the crosstalk between 20 key virulence-related TFs. Using chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq), as well as RNA-seq, we identify...
Paper Details
Title
An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
Published Date
Jul 3, 2019
Journal
Volume
10
Issue
1
Pages
2931 - 2931
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