<p>Self-microemulsifying drug delivery system (SMEDDS) for improved oral delivery and photostability of methotrexate</p>
Volume: Volume 14, Pages: 4949 - 4960
Published: Jul 1, 2019
Abstract
Purpose: The objective of this study was to exploit a novel methotrexate (MTX)-loaded solid self-microemulsifying drug delivery system (SMEDDS) with enhanced bioavailability and photostability. Materials and methods: The optimized liquid SMEDDS was composed of castor oil, Tween ® 80, and Plurol ® diisostearique at a voluminous ratio of 27:63:10. The solid SMEDDS was formulated by spray drying liquid SMEDDS with the solid carrier (calcium...
Paper Details
Title
<p>Self-microemulsifying drug delivery system (SMEDDS) for improved oral delivery and photostability of methotrexate</p>
Published Date
Jul 1, 2019
Volume
Volume 14
Pages
4949 - 4960
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