Bromodomain inhibitor I-BET151 suppresses immune responses during fungal-immune interaction.

Volume: 49, Issue: 11, Pages: 2044 - 2050
Published: Nov 1, 2019
Abstract
Changes in the epigenetic landscape of immune cells are a crucial component of gene activation during the induction of inflammatory responses, therefore it has been hypothesized that epigenetic modulation could be employed to restore homeostasis in inflammatory scenarios. Fungal pathogens cause a large burden of morbidity and even mortality due to the hyperinflammatory processes that induce mucosal, allergic or systemic infections. Bromodomain...
Paper Details
Title
Bromodomain inhibitor I-BET151 suppresses immune responses during fungal-immune interaction.
Published Date
Nov 1, 2019
Volume
49
Issue
11
Pages
2044 - 2050
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