AB0133 HUMAN UMBILICAL CORD-DERIVED MESENCHYMAL STEM CELLS AMELIORATE COLLAGEN-INDUCED ARTHRITIS VIA IMMUNOMODULATORY EFFECT ON T LYMPHOCYTES

Background:

Rheumatoid arthritis (RA) is an autoimmune disease that results in cartilage and bone destruction. Overactivation of T lymphocytes and imbalance of T lymphocyte subsets are closely related to the occurrence and development of RA. These have become important mechanisms of inflammation, immune activation, and bone destruction. RA treatment ideally involves regulation of immune abnormalities and maintenance of immune...