Phenotypic consequences of RNA polymerase dysregulation in Escherichia coli
Abstract
Many bacterial adaptive responses to changes in growth conditions due to biotic and abiotic factors involve reprogramming of gene expression at the transcription level. The bacterial RNA polymerase (RNAP), which catalyzes transcription, can thus be considered as the major mediator of cellular adaptive strategies. But how do bacteria respond if a stress factor directly compromises the activity of the RNAP? We used a phage-derived small protein to...
Paper Details
Title
Phenotypic consequences of RNA polymerase dysregulation in Escherichia coli
Published Date
Aug 23, 2017
Journal
Volume
45
Issue
19
Pages
11131 - 11143
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