p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes
Volume: 12, Issue: 1
Published: Jun 4, 2019
Abstract
The transcription factor p63 regulates epidermal genes and the enhancer landscape in skin keratinocytes. Its molecular function in controlling the chromatin structure is, however, not yet completely understood. Here, we integrated multi-omics profiles, including the transcriptome, transcription factor DNA-binding and chromatin accessibility, in skin keratinocytes isolated from EEC syndrome patients carrying p63 mutations, to examine the role of...
Paper Details
Title
p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes
Published Date
Jun 4, 2019
Volume
12
Issue
1
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