FRI0657 METABOLIC SYNDROME PRECEDES THE ONSET OF HIP AND KNEE PAIN AND THE RISK IS NOT MODIFIED BY DIET OR CHANGES IN BMI

Background

Excess weight and components of the metabolic syndrome have been associated with knee osteoarthritis (OA). However, the precise timing of when this risk operates in the natural history of the disease is unknown. An understanding of the sequence in which risk factors operate in OA is important for delivering effective preventative interventions.

Objectives

We examined longitudinal data from a large prospective...