Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.
Abstract
Recent technical advancements have facilitated the mapping of epigenomes at single-cell resolution; however, the throughput and quality of these methods have limited their widespread adoption. Here we describe a high-quality (105 nuclear fragments per cell) droplet-microfluidics-based method for single-cell profiling of chromatin accessibility. We use this approach, named 'droplet single-cell assay for transposase-accessible chromatin using...
Paper Details
Title
Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.
Published Date
Jun 24, 2019
Journal
Volume
37
Issue
8
Pages
916 - 924
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History