Prognostic Impact of Canonical TGF-β Signaling in Urothelial Bladder Cancer
Abstract
Background and objectives: Dysregulation of TGF-β signaling plays multiple roles in cancer development and progression. In the canonical TGF-β pathway, TGF-β regulates the expression of hundreds of target genes via interaction with Smads, signal transducers and transcriptional modulators. We evaluated the association of TGF-β1, Smad2, and Smad4, the key components of canonical TGFβ pathway, with clinicopathologic characteristics of urothelial...
Paper Details
Title
Prognostic Impact of Canonical TGF-β Signaling in Urothelial Bladder Cancer
Published Date
Jun 24, 2019
Journal
Volume
55
Issue
6
Pages
302 - 302
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