Ca²⁺ movement and cytotoxicity induced by the pyrethroid pesticide bifenthrin in human prostate cancer cells

Bifenthrin, a commonly used pyrethroid pesticide, evokes various toxicological effects in different models. However, the effect of bifenthrin on cytosolic-free Ca 2+ level ([Ca 2+ ] i ) and cytotoxicity in human prostate cancer cells is unclear. This study examined whether bifenthrin altered Ca 2+ homeostasis and cell viability in PC3 human prostate cancer cells. [Ca 2+ ] i in suspended cells were measured using the fluorescent Ca 2+ -sensitive...