Review paper
IGF signalling in germ cells and testicular germ cell tumours: roles and therapeutic approaches
Abstract
The insulin-like growth factor (IGF) axis plays key roles in normal tissue growth and development as well as in the progression of several tumour types and their subsequent growth and progression to a metastatic phenotype. This review explores the role of IGF system in normal germ cell development and function in addition to examining the evidence for deregulation of IGF signalling in cancer, with particular relevance to evidence supporting a...
Paper Details
Title
Published Date
Jun 9, 2019
Journal
Volume
7
Issue
4
Pages
536 - 544
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