Validation of early drain removal after pancreatoduodenectomy based on fistula risk score stratification: A population-based analysis

Background: Recent studies on postoperative pancreatic fistula (POPF) prevention following pancreatoduodenectomy (PD) have proposed omission of perioperative drains for negligible/low-risk patients and early drain removal (≤POD3) for moderate/high-risk patients with POD1 drain amylase levels ≤5000 U/L. We sought to validate this algorithm using a nationwide cohort. Methods: The ACS-NSQIP targeted pancreatectomy database from 2014-2016 was...