Mitochondrial miR-762 regulates apoptosis and myocardial infarction by impairing ND2
Abstract
Mitochondrial dysfunction plays a major role in the pathogenesis of cardiovascular diseases. MicroRNAs (miRNAs) are small RNAs that act as negative regulators of gene expression, but how miRNAs affect mitochondrial function in the heart is unclear. Using a miRNA microarray assay, we found that miR-762 predominantly translocated in the mitochondria and was significantly upregulated upon anoxia/reoxygenation (A/R) treatment. Knockdown of...
Paper Details
Title
Mitochondrial miR-762 regulates apoptosis and myocardial infarction by impairing ND2
Published Date
Jun 24, 2019
Journal
Volume
10
Issue
7
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