The additive effect of allopregnanolone on ghrelin's orexigenic effect in rats
Abstract
The progesterone metabolite, allopregnanolone (AlloP), is a GABAA receptor modulating steroid and is known to have orexigenic and pro-obesity effects. The neurobiological mechanisms underpinning these effects are most likely due to enhanced GABAergic signaling in the lateral arcuate nucleus (ARC) and medial paraventricular nucleus (PVN) of the hypothalamus. Inspired by the finding that GABAergic signaling is also important for the orexigenic...
Paper Details
Title
The additive effect of allopregnanolone on ghrelin's orexigenic effect in rats
Published Date
Aug 1, 2019
Journal
Volume
76
Pages
101937 - 101937
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