Shaping Striated Muscles with Ubiquitin Proteasome System in Health and Disease

Volume: 25, Issue: 9, Pages: 760 - 774
Published: Sep 1, 2019
Abstract
For long-lived contractile cells, such as striated muscle cells, maintaining proteome integrity is a challenging task. These cells require hundreds of components that must be properly synthesized, folded, and incorporated into the basic contractile unit, the sarcomere. Muscle protein quality control in cells is mainly guaranteed by the ubiquitin-proteasome system (UPS), the lysosome-autophagy system, and various molecular chaperones. Recent...
Paper Details
Title
Shaping Striated Muscles with Ubiquitin Proteasome System in Health and Disease
Published Date
Sep 1, 2019
Volume
25
Issue
9
Pages
760 - 774
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