Brain and psychological determinants of placebo pill response in chronic pain patients
Abstract
The placebo response is universally observed in clinical trials of pain treatments, yet the individual characteristics rendering a patient a 'placebo responder' remain unclear. Here, in chronic back pain patients, we demonstrate using MRI and fMRI that the response to placebo 'analgesic' pills depends on brain structure and function. Subcortical limbic volume asymmetry, sensorimotor cortical thickness, and functional coupling of prefrontal...
Paper Details
Title
Brain and psychological determinants of placebo pill response in chronic pain patients
Published Date
Sep 12, 2018
Journal
Volume
9
Issue
1
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