ATR is required to complete meiotic recombination in mice
Abstract
Precise execution of recombination during meiosis is essential for forming chromosomally-balanced gametes. Meiotic recombination initiates with the formation and resection of DNA double-strand breaks (DSBs). Cellular responses to meiotic DSBs are critical for efficient repair and quality control, but molecular features of these remain poorly understood, particularly in mammals. Here we report that the DNA damage response protein kinase ATR is...
Paper Details
Title
ATR is required to complete meiotic recombination in mice
Published Date
Jul 5, 2018
Journal
Volume
9
Issue
1
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