Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
Abstract
One of the biggest hurdles for the development of metabolism-targeted therapies is to identify the responsive tumor subsets. However, the metabolic vulnerabilities for most human cancers remain unclear. Establishing the link between metabolic signatures and the oncogenic alterations of receptor tyrosine kinases (RTK), the most well-defined cancer genotypes, may precisely direct metabolic intervention to a broad patient population. By integrating...
Paper Details
Title
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
Published Date
Jun 20, 2019
Journal
Volume
10
Issue
1
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