Identification of dicarbonyl and L-xylulose reductase as a therapeutic target in human chronic kidney disease
Abstract
An imbalance of nephroprotective factors and renal damaging molecules contributes to development and progression of chronic kidney disease (CKD). We investigated associations of renoprotective factor gene expression patterns with CKD severity and outcome. Gene expression profiles of 197 previously reported renoprotective factors were analyzed in a discovery cohort in renal biopsies of 63 CKD patients. Downregulation of dicarbonyl and L-xylulose...
Paper Details
Title
Identification of dicarbonyl and L-xylulose reductase as a therapeutic target in human chronic kidney disease
Published Date
Jun 20, 2019
Journal
Volume
4
Issue
12
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History