Original paper
Signatures of Long-Term Balancing Selection in Human Genomes
Abstract
Balancing selection maintains advantageous diversity in populations through various mechanisms. Although extensively explored from a theoretical perspective, an empirical understanding of its prevalence and targets lags behind our knowledge of positive selection. Here, we describe the Non-central Deviation (NCD), a simple yet powerful statistic to detect long-term balancing selection (LTBS) that quantifies how close frequencies are to...
Paper Details
Title
Signatures of Long-Term Balancing Selection in Human Genomes
Published Date
Mar 1, 2018
Journal
Volume
10
Issue
3
Pages
939 - 955
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Notes
History