The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway
Abstract
Carvedilol, a third generation beta blocker, is in clinical use for heart failure patients. However, besides adrenergic receptor blockade, the pharmacological effects of carvedilol on cardiomyocytes remain unknown. AMP-activated protein kinase (AMPK) is an emerging target recognized for heart failure treatment. The mechanical properties and intracellular Ca2+ properties were measured in isolated cardiomyocyte contractile functions in response to...
Paper Details
Title
The cardioprotective effects of carvedilol on ischemia and reperfusion injury by AMPK signaling pathway
Published Date
Sep 1, 2019
Volume
117
Pages
109106 - 109106
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