Claudin as a Novel Target for Drug Delivery System

Recent remarkable progress in genomic novel drug discovery enables us to prepare drug candidates with tremendous diversity in a high-throughput-manner. In clinical use of these candidates, they should be effectively delivered to a target-tissue in body. But delivery systems suitable for the high-throughput discovery of drugs have never been established. Tight junctions (TJs) play a pivotal role in compartmentation of each tissues and maintenance...