Aerobic and resistance exercise training reverses age‐dependent decline in NAD+salvage capacity in human skeletal muscle

Volume: 7, Issue: 12
Published: Jun 1, 2019
Abstract
Aging decreases skeletal muscle mass and strength, but aerobic and resistance exercise training maintains skeletal muscle function. NAD+ is a coenzyme for ATP production and a required substrate for enzymes regulating cellular homeostasis. In skeletal muscle, NAD+ is mainly generated by the NAD+ salvage pathway in which nicotinamide phosphoribosyltransferase (NAMPT) is rate-limiting. NAMPT decreases with age in human skeletal muscle, and aerobic...
Paper Details
Title
Aerobic and resistance exercise training reverses age‐dependent decline in NAD+salvage capacity in human skeletal muscle
Published Date
Jun 1, 2019
Volume
7
Issue
12
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