Increased cardiorespiratory fitness and skeletal muscle size following single-leg knee extension exercise training

It is unclear to what extent an improved skeletal muscle phenotype influences maximal aerobic capacity (VO2max) when changes in cardiopulmonary function are limited. Thus, to primarily target skeletal muscle adaptations, we employed an alternating single-leg knee extension exercise training protocol and evaluated the impact on skeletal muscle morphology and whole-body exercise capacity.Eight sedentary volunteers (20±1 years; VO2max: 38.4±2.6...