Traditional Diet Influences Erythrocyte Fatty Acids Differentially Across Genetic Variants of Fatty Acid Metabolism: The Greenlandic Inuit Health in Transition Cohort (FS11-02-19)

Traditional foods of the Greenlandic Inuit are mainly fish and marine mammals. Hence, the high fat content and unique dietary fatty acid (FA) profile may affect circulating FA profiles. Moreover, it is shown that the rs80356779 variant of the carnitine palmitoyl-transferase 1A (CPT1A) gene, involved in FA transportation, underwent positive selection in Inuit ancestors. The variant is associated with circulating FA profiles in Inuit, and...