Reactive oxygen species are involved in eosinophil extracellular traps release and in airway inflammation in asthma

In asthma, there are high levels of inflammatory mediators, reactive oxygen species (ROS), and eosinophil extracellular traps (EETs) formation in airway. Here, we attempted to investigate the ROS involvement in EETs release and airway inflammation in OVA‐challenged mice. Before the intranasal challenge with ovalbumin (OVA), animals were treated with two ROS inhibitors, N ‐acetylcysteine (NAC) or diphenyleneiodonium (DPI). We showed that NAC...