Original paper
Overlap graph-based generation of haplotigs for diploids and polyploids
Abstract
Haplotype-aware genome assembly plays an important role in genetics, medicine and various other disciplines, yet generation of haplotype-resolved de novo assemblies remains a major challenge. Beyond distinguishing between errors and true sequential variants, one needs to assign the true variants to the different genome copies. Recent work has pointed out that the enormous quantities of traditional NGS read data have been greatly underexploited...
Paper Details
Title
Overlap graph-based generation of haplotigs for diploids and polyploids
Published Date
Apr 17, 2019
Journal
Volume
35
Issue
21
Pages
4281 - 4289
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Notes
History