Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury.
Abstract
Background & Aims null Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, a key downstream effector of the Hippo pathway, is essential for determining cell fate and maintaining homeostasis in the liver. We aimed to elucidate its role in IRI. null Methods null The role of YAP/Hippo signaling was systematically studied in biopsy specimens from 60 patients after...
Paper Details
Title
Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury.
Published Date
Oct 1, 2019
Journal
Volume
71
Issue
4
Pages
719 - 730
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Notes
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