IDENTIFICATION OF NOVEL MICRORNAS ASSOCIATED ATHEROSCLEROTIC LESION FORMATION IN THE AORTA OF HYPERCHOLESTEROLEMIC APOE-/- MICE

Objective: Evidence is accumulating that microRNAs (miRNAs), members of the non-coding RNA family, may be effective biomarkers and therapeutic targets in atherosclerosis. The aim of this study was to identify novel miRNA expression patterns underlying vascular inflammation and oxidative stress associated with atheroma formation in human and experimental atherosclerosis. Design and method: Human non-atherosclerotic (superior thyroid artery) and...