Anti−PD-1 Immunotherapy May Induce Interstitial Nephritis With Increased Tubular Epithelial Expression of PD-L1

Volume: 4, Issue: 8, Pages: 1152 - 1160
Published: Aug 1, 2019
Abstract
Novel anticancer therapies include anti-programmed cell death protein-1 (PD-1) and anti-programmed death ligand-1 (PD-L1) drugs. These novel medications have side effects in different organs, including the kidney. The most common adverse effect in the kidney is acute interstitial nephritis (AIN). No diagnostic criteria are available to distinguish AIN associated with anti-PD-1 therapy from other AINs.Kidney biopsy specimens from patients on...
Paper Details
Title
Anti−PD-1 Immunotherapy May Induce Interstitial Nephritis With Increased Tubular Epithelial Expression of PD-L1
Published Date
Aug 1, 2019
Volume
4
Issue
8
Pages
1152 - 1160
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