Bifunctional Fluorescent/Raman Nanoprobe for the Early Detection of Amyloid
Abstract
One of the pathological hallmarks of Alzheimer’s disease (AD) is the abnormal aggregation of amyloid beta (Aβ) peptides. Therefore the detection of Aβ peptides and imaging of amyloid plaques are considered as promising diagnostic methods for AD. Here we report a bifunctional nanoprobe prepared by conjugating gold nanoparticles (AuNPs) with Rose Bengal (RB) dye. RB is chosen due to its unique Raman fingerprints and affinity with Aβ peptides....
Paper Details
Title
Bifunctional Fluorescent/Raman Nanoprobe for the Early Detection of Amyloid
Published Date
Jun 11, 2019
Journal
Volume
9
Issue
1
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